The outcome and quality of life of chronic myeloid leukemia (CML) patients has remarkably changed with the treatment of tyrosine kinase inhibitors (TKIs).Currently, hematopoietic stem cell transplantation (HSCT) is considered mainly as a third line salvage Modern POP therapy in cases of TKIs resistance or intolerance.Here we describe a patient with
Multi-Modal Sleep Stage Classification With Two-Stream Encoder-Decoder
Sleep staging serves as a fundamental assessment for sleep quality measurement and sleep disorder diagnosis.Although current deep learning approaches have successfully integrated multimodal sleep signals, enhancing the accuracy of automatic sleep staging, certain challenges remain, as follows: 1) optimizing the utilization of multi-modal informatio
Budget impact analysis of routinely using whole-genomic sequencing of six multidrug-resistant bacterial pathogens in Queensland, Australia
Objective To predict the cost and health effects of routine use of whole-genome sequencing (WGS) of bacterial pathogens compared with those of standard of care.Design Budget impact analysis was performed over the following 5 years.Data were primarily from sequencing results on clusters of multidrug-resistant organisms across 27 hospitals.Model inpu